1AK2

ADENYLATE KINASE ISOENZYME-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004017	molecular_function	adenylate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006172	biological_process	ADP biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016776	molecular_function	phosphotransferase activity, phosphate group as acceptor
A	0019205	molecular_function	nucleobase-containing compound kinase activity
A	0036126	cellular_component	sperm flagellum
A	0046033	biological_process	AMP metabolic process
A	0046034	biological_process	ATP metabolic process
A	0046940	biological_process	nucleoside monophosphate phosphorylation
A	0097226	cellular_component	sperm mitochondrial sheath

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 301

Chain	Residue
A	PRO24
A	GLY26
A	ALA27
A	GLY28
A	LYS29
A	GLY30

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Functional Information from PROSITE/UniProt

site_id	PS00113
Number of Residues	12
Details	ADENYLATE_KINASE Adenylate kinase signature. FLLDGFPRtvrQ

Chain	Residue	Details
A	PHE97-GLN108

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03168

Chain	Residue	Details
A	ALA27
A	LEU188
A	THR216
A	GLY48
A	ALA53
A	LEU74
A	PHE102
A	ALA109
A	LEU144
A	TYR153
A	SER177

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P54819

Chain	Residue	Details
A	ALA1

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P54819

Chain	Residue	Details
A	GLU60
A	LEU135

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q9WTP6

Chain	Residue	Details
A	LYS64
A	ASN95

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9WTP6

Chain	Residue	Details
A	ALA183

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P54819

Chain	Residue	Details
A	PRO197

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	6
Details	Annotated By Reference To The Literature 1zio

Chain	Residue	Details
A	ARG187
A	ASP179
A	ARG143
A	ASP178
A	ARG176
A	LYS29

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site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1zio

Chain	Residue	Details
A	ARG143
A	ASP49
A	ASP167
A	LYS29

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