Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004156 | molecular_function | dihydropteroate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0009410 | biological_process | response to xenobiotic stimulus |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| A | 0046656 | biological_process | folic acid biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 283 |
| Chain | Residue |
| A | ASN22 |
| A | ARG63 |
| A | ARG255 |
| A | HIS257 |
| A | HOH320 |
| A | HOH323 |
| A | HOH360 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 284 |
| Chain | Residue |
| A | HOH290 |
| A | HOH313 |
| A | SER222 |
| A | ARG235 |
Functional Information from PROSITE/UniProt
| site_id | PS00792 |
| Number of Residues | 16 |
| Details | DHPS_1 Dihydropteroate synthase signature 1. VmGILNvTpDSFsDgG |
| Chain | Residue | Details |
| A | VAL17-GLY32 | |
| site_id | PS00793 |
| Number of Residues | 14 |
| Details | DHPS_2 Dihydropteroate synthase signature 2. GAtIIDVGGesTrP |
| Chain | Residue | Details |
| A | GLY51-PRO64 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 252 |
| Details | Domain: {"description":"Pterin-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00334","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WND1","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0AC11","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9187658","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1AJ2","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37419898","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7TQ1","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1aj0 |
| Chain | Residue | Details |
| A | ASN22 | |
| A | ARG255 | |
| A | ARG63 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 394 |
| Chain | Residue | Details |
| A | LYS221 | activator |
| A | ARG255 | activator |
1AJZ
