Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016740 | molecular_function | transferase activity |
| A | 0036440 | molecular_function | citrate synthase activity |
| A | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016740 | molecular_function | transferase activity |
| B | 0036440 | molecular_function | citrate synthase activity |
| B | 0046912 | molecular_function | acyltransferase activity, acyl groups converted into alkyl on transfer |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE COA A 3000 |
| Chain | Residue |
| A | LYS254 |
| A | LYS256 |
| A | ILE257 |
| A | MET258 |
| A | GLY259 |
| A | ALA260 |
| A | GLY261 |
| A | HIS262 |
| A | ARG263 |
| A | LYS305 |
| A | ILE307 |
| A | ASN310 |
| A | CIT1000 |
| A | HOH3132 |
| A | HOH3166 |
| A | HOH3194 |
| B | ARG353 |
| B | HOH4024 |
| A | ILE222 |
| A | HIS223 |
| A | ALA226 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE COA B 4000 |
| Chain | Residue |
| A | ARG353 |
| B | ILE222 |
| B | HIS223 |
| B | ALA226 |
| B | LYS256 |
| B | ILE257 |
| B | MET258 |
| B | GLY259 |
| B | ALA260 |
| B | GLY261 |
| B | ARG263 |
| B | LYS305 |
| B | ILE307 |
| B | ASN310 |
| B | CIT2000 |
| B | HOH4005 |
| B | HOH4012 |
| B | HOH4110 |
| B | HOH4233 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CIT A 1000 |
| Chain | Residue |
| A | HIS188 |
| A | ASN191 |
| A | HIS223 |
| A | GLY224 |
| A | HIS262 |
| A | ARG271 |
| A | ASP312 |
| A | ARG337 |
| A | COA3000 |
| A | HOH3025 |
| A | HOH3035 |
| A | HOH3194 |
| B | ARG356 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CIT B 2000 |
| Chain | Residue |
| A | ARG356 |
| B | HIS188 |
| B | ASN191 |
| B | HIS223 |
| B | GLY224 |
| B | HIS262 |
| B | ARG271 |
| B | ASP312 |
| B | ARG337 |
| B | COA4000 |
| B | HOH4041 |
| B | HOH4110 |
| B | HOH4142 |
| site_id | ACA |
| Number of Residues | 3 |
| Details | CATALYTIC RESIDUES. |
| Chain | Residue |
| A | HIS223 |
| A | HIS262 |
| A | ASP312 |
| site_id | ACB |
| Number of Residues | 3 |
| Details | CATALYTIC RESIDUES. |
| Chain | Residue |
| B | HIS223 |
| B | HIS262 |
| B | ASP312 |
Functional Information from PROSITE/UniProt
| site_id | PS00480 |
| Number of Residues | 13 |
| Details | CITRATE_SYNTHASE Citrate synthase signature. GAGHrVy.KtyDPR |
| Chain | Residue | Details |
| A | GLY259-ARG271 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10117","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 9254593, 9036855, 16830149, 2337600, 8718855 |
| Chain | Residue | Details |
| A | HIS223 | |
| A | HIS262 | |
| A | ASP312 | |
| A | SER193 | |
