1AGI

CRYSTAL STRUCTURE OF BOVINE ANGIOGENIN AT 1.5 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001525	biological_process	angiogenesis
A	0001541	biological_process	ovarian follicle development
A	0001666	biological_process	response to hypoxia
A	0001938	biological_process	positive regulation of endothelial cell proliferation
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003779	molecular_function	actin binding
A	0004519	molecular_function	endonuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0005102	molecular_function	signaling receptor binding
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005604	cellular_component	basement membrane
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005730	cellular_component	nucleolus
A	0008201	molecular_function	heparin binding
A	0009303	biological_process	rRNA transcription
A	0017148	biological_process	negative regulation of translation
A	0019731	biological_process	antibacterial humoral response
A	0023052	biological_process	signaling
A	0030041	biological_process	actin filament polymerization
A	0030154	biological_process	cell differentiation
A	0030426	cellular_component	growth cone
A	0031410	cellular_component	cytoplasmic vesicle
A	0032311	cellular_component	angiogenin-PRI complex
A	0043025	cellular_component	neuronal cell body
A	0045087	biological_process	innate immune response
A	0048662	biological_process	negative regulation of smooth muscle cell proliferation
A	0050714	biological_process	positive regulation of protein secretion
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide

Functional Information from PDB Data

site_id	PRS
Number of Residues	17
Details

Chain	Residue
A	GLU59
A	ASP60
A	ARG61
A	ASN62
A	GLY63
A	GLN64
A	PRO65
A	TYR66
A	ARG67
A	GLY68
A	ASP69
A	LEU70
A	ARG71
A	GLU109
A	ASN110
A	GLY111
A	LEU112

---

site_id	RAS
Number of Residues	12
Details

Chain	Residue
A	GLN13
A	GLU118
A	SER119
A	PHE120
A	HIS14
A	LYS41
A	ARG43
A	ASN44
A	THR45
A	HIS115
A	PHE116
A	ASP117

---

Functional Information from PROSITE/UniProt

site_id	PS00127
Number of Residues	7
Details	RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKdrNTF

Chain	Residue	Details
A	CYS40-PHE46

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor

Chain	Residue	Details
A	THR37

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
A	GLN64

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1rbn

Chain	Residue	Details
A	HIS14
A	PHE116
A	HIS115
A	LYS41

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1rbn

Chain	Residue	Details
A	HIS14
A	HIS115
A	LYS41

---