1AG1

MONOHYDROGEN PHOSPHATE BINDING TO TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE

Functional Information from GO Data

Chain	GOid	namespace	contents
O	0004807	molecular_function	triose-phosphate isomerase activity
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006094	biological_process	gluconeogenesis
O	0006096	biological_process	glycolytic process
O	0016853	molecular_function	isomerase activity
O	0019563	biological_process	glycerol catabolic process
O	0020015	cellular_component	glycosome
O	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process
T	0004807	molecular_function	triose-phosphate isomerase activity
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006094	biological_process	gluconeogenesis
T	0006096	biological_process	glycolytic process
T	0016853	molecular_function	isomerase activity
T	0019563	biological_process	glycerol catabolic process
T	0020015	cellular_component	glycosome
T	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 T 600

Chain	Residue
T	LYS13
T	HOH743
T	ALA171
T	GLY173
T	SER213
T	GLY234
T	GLY235
T	HOH639
T	HOH713
T	HOH731

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Functional Information from PROSITE/UniProt

site_id	PS00171
Number of Residues	11
Details	TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG

Chain	Residue	Details
O	ALA165-GLY175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Electrophile"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton acceptor"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
O	LYS13
O	HIS95
O	ASN11
O	GLU167
O	GLY173

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site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
T	LYS13
T	HIS95
T	ASN11
T	GLU167
T	GLY173

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