Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 276 |
| Chain | Residue |
| A | GLN2 |
| A | ASP41 |
| A | LEU75 |
| A | ASN77 |
| A | THR79 |
| A | VAL81 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DIO A 342 |
| Chain | Residue |
| A | ASN25 |
| A | LYS136 |
| A | ASP140 |
| A | TYR171 |
| A | ASP172 |
| A | SER173 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DIO A 343 |
| Chain | Residue |
| A | PRO5 |
| A | TYR6 |
| A | GLY53 |
| A | GLY204 |
| A | VAL205 |
| A | TYR206 |
| A | TYR256 |
| A | HOH280 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DIO A 344 |
| Chain | Residue |
| A | PHE50 |
| A | SER109 |
| A | GLU112 |
| A | PRO210 |
| A | THR211 |
| A | THR213 |
| A | HOH338 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DIO A 345 |
| Chain | Residue |
| A | ALA52 |
| A | GLY53 |
| A | TYR256 |
| A | HOH331 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DIO A 346 |
| Chain | Residue |
| A | ASN62 |
| A | HIS64 |
| A | TYR209 |
| A | LEU217 |
| A | DIO347 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DIO A 347 |
| Chain | Residue |
| A | ASN62 |
| A | HIS64 |
| A | GLY100 |
| A | HOH334 |
| A | DIO346 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DIO A 348 |
| Chain | Residue |
| A | ALA1 |
| A | SER184 |
| A | THR255 |
| site_id | ACT |
| Number of Residues | 3 |
| Details | |
| Chain | Residue |
| A | ASP32 |
| A | HIS64 |
| A | SER221 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAVLDTGIqasH |
| Chain | Residue | Details |
| A | VAL28-HIS39 | |
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThVAGtVAA |
| Chain | Residue | Details |
| A | HIS64-ALA74 | |
| site_id | PS00138 |
| Number of Residues | 11 |
| Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAsPhVAG |
| Chain | Residue | Details |
| A | GLY219-GLY229 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 268 |
| Details | Domain: {"description":"Peptidase S8","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8512925","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1sca |
| Chain | Residue | Details |
| A | SER221 | |
| A | HIS64 | |
| A | ASP32 | |
