1AEC
CRYSTAL STRUCTURE OF ACTINIDIN-E-64 COMPLEX+
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE E64 A 219 |
| Chain | Residue |
| A | GLN19 |
| A | GLY68 |
| A | TYR69 |
| A | ASN88 |
| A | ASP161 |
| A | HIS162 |
| A | HOH272 |
| A | HOH305 |
| A | HOH481 |
| A | HOH485 |
| A | GLY23 |
| A | GLY24 |
| A | CYS25 |
| A | TRP26 |
| A | ASN61 |
| A | ARG63 |
| A | ASN66 |
| A | GLY67 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGeCGGCWAfSA |
| Chain | Residue | Details |
| A | GLN19-ALA30 |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. IDHAVTIVGYG |
| Chain | Residue | Details |
| A | ILE160-GLY170 |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvKNSWdttWGeeGYMrI |
| Chain | Residue | Details |
| A | TYR177-ILE196 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10088","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1606141","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1AEC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10089","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10090","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"1606141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AEC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | ASN182 | |
| A | CYS25 | |
| A | HIS162 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | GLN19 | |
| A | CYS25 | |
| A | HIS162 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | ASN182 | |
| A | GLN19 | |
| A | HIS162 |
