Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001507 | biological_process | acetylcholine catabolic process in synaptic cleft |
A | 0003990 | molecular_function | acetylcholinesterase activity |
A | 0004104 | molecular_function | cholinesterase activity |
A | 0005615 | cellular_component | extracellular space |
A | 0005886 | cellular_component | plasma membrane |
A | 0006581 | biological_process | acetylcholine catabolic process |
A | 0019695 | biological_process | choline metabolic process |
A | 0043083 | cellular_component | synaptic cleft |
A | 0045202 | cellular_component | synapse |
A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
A | 0098552 | cellular_component | side of membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE DME A 999 |
Chain | Residue |
A | HIS440 |
A | TYR70 |
A | TRP84 |
A | TYR121 |
A | TRP279 |
A | PHE330 |
site_id | DME |
Number of Residues | 4 |
Details | |
Chain | Residue |
A | SER200 |
A | HIS440 |
A | GLU327 |
A | DME999 |
Functional Information from PROSITE/UniProt
site_id | PS00122 |
Number of Residues | 16 |
Details | CARBOXYLESTERASE_B_1 Carboxylesterases type-B serine active site. FGGdpktVtIfGeSAG |
Chain | Residue | Details |
A | PHE187-GLY202 | |
site_id | PS00941 |
Number of Residues | 11 |
Details | CARBOXYLESTERASE_B_2 Carboxylesterases type-B signature 2. EDCLYLNIWvP |
Chain | Residue | Details |
A | GLU92-PRO102 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Acyl-ester intermediate |
Chain | Residue | Details |
A | SER200 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | GLU327 | |
A | HIS440 | |
Chain | Residue | Details |
A | ASN59 | |
Chain | Residue | Details |
A | ASN416 | |
Chain | Residue | Details |
A | ASN457 | |
A | ASN533 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1qe3 |
Chain | Residue | Details |
A | SER200 | |
A | HIS440 | |
A | GLU327 | |