Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0030598 | molecular_function | rRNA N-glycosylase activity |
Functional Information from PDB Data
| site_id | ACT |
| Number of Residues | 10 |
| Details | ACTIVE SITE CLEFT OF ABRIN-A A-CHAIN CONTAINS 5 INVARIANT AND 5 CONSERVED RESIDUES. THE FIRST 5 RESIDUES IN THE LIST ARE INVARIANT RESIDUES. |
| Chain | Residue |
| A | TYR74 |
| A | ASN196 |
| A | TYR113 |
| A | GLU164 |
| A | ARG167 |
| A | TRP198 |
| A | ASN72 |
| A | ARG124 |
| A | GLN160 |
| A | GLU195 |
| site_id | GL1 |
| Number of Residues | 2 |
| Details | THE FIRST GLYCOSYLATION SITE OF ABRIN-A B-CHAIN BINDS N-ACETYLGLYCOSAMINE, NDG1, OF FIRST SUGAR CHAIN PRESENTED WITH INSERTION CODE C. |
| Chain | Residue |
| B | ASN100 |
| B | TYR130 |
| site_id | GL2 |
| Number of Residues | 1 |
| Details | THE SECOND GLYCOSYLATION SITE OF ABRIN-A B-CHAIN BINDS N-ACETYLGLYCOSAMINES, NDG1 AND NDG2, OF THE SECOND SUGAR CHAIN PRESENTED WITH INSERTION CODE D. |
| site_id | SU1 |
| Number of Residues | 2 |
| Details | THE FIRST SUGAR BINDING SITE OF ABRIN-A B-CHAIN BINDS MANNOSE, MAN4, OF THE SUGAR CHAIN WHICH SYMMETRICALLY RELATED TO THE FIRST SUGAR CHAIN IDENTIFIED WITH INSERTION CODE C. |
| site_id | SU2 |
| Number of Residues | 1 |
| Details | THE POTENTIAL SECOND SUGAR BINDING SITE OF ABRIN-A B-CHAIN. THIS IS NOT CONFIRMED BY CURRENT STRUCTURE. |
Functional Information from PROSITE/UniProt
| site_id | PS00275 |
| Number of Residues | 17 |
| Details | SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMVaEAARFRyISnrV |
| Chain | Residue | Details |
| A | ILE159-VAL175 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU164 | |
| B | ASN140 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|Ref.2 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | a catalytic site defined by CSA, PubMed 7608980, 1433290 |
| Chain | Residue | Details |
| A | GLU164 | |
| A | ARG167 | |
