Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1A9C

GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0003934	molecular_function	GTP cyclohydrolase I activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006729	biological_process	tetrahydrobiopterin biosynthetic process
A	0006730	biological_process	one-carbon metabolic process
A	0008270	molecular_function	zinc ion binding
A	0008616	biological_process	tRNA queuosine(34) biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0046654	biological_process	tetrahydrofolate biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0003934	molecular_function	GTP cyclohydrolase I activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006729	biological_process	tetrahydrobiopterin biosynthetic process
B	0006730	biological_process	one-carbon metabolic process
B	0008270	molecular_function	zinc ion binding
B	0008616	biological_process	tRNA queuosine(34) biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0046654	biological_process	tetrahydrofolate biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0003934	molecular_function	GTP cyclohydrolase I activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006729	biological_process	tetrahydrobiopterin biosynthetic process
C	0006730	biological_process	one-carbon metabolic process
C	0008270	molecular_function	zinc ion binding
C	0008616	biological_process	tRNA queuosine(34) biosynthetic process
C	0016787	molecular_function	hydrolase activity
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0046654	biological_process	tetrahydrofolate biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0003934	molecular_function	GTP cyclohydrolase I activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006729	biological_process	tetrahydrobiopterin biosynthetic process
D	0006730	biological_process	one-carbon metabolic process
D	0008270	molecular_function	zinc ion binding
D	0008616	biological_process	tRNA queuosine(34) biosynthetic process
D	0016787	molecular_function	hydrolase activity
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0046654	biological_process	tetrahydrofolate biosynthetic process
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0003934	molecular_function	GTP cyclohydrolase I activity
E	0005525	molecular_function	GTP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006729	biological_process	tetrahydrobiopterin biosynthetic process
E	0006730	biological_process	one-carbon metabolic process
E	0008270	molecular_function	zinc ion binding
E	0008616	biological_process	tRNA queuosine(34) biosynthetic process
E	0016787	molecular_function	hydrolase activity
E	0032991	cellular_component	protein-containing complex
E	0042802	molecular_function	identical protein binding
E	0046654	biological_process	tetrahydrofolate biosynthetic process
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0003934	molecular_function	GTP cyclohydrolase I activity
F	0005525	molecular_function	GTP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006729	biological_process	tetrahydrobiopterin biosynthetic process
F	0006730	biological_process	one-carbon metabolic process
F	0008270	molecular_function	zinc ion binding
F	0008616	biological_process	tRNA queuosine(34) biosynthetic process
F	0016787	molecular_function	hydrolase activity
F	0032991	cellular_component	protein-containing complex
F	0042802	molecular_function	identical protein binding
F	0046654	biological_process	tetrahydrofolate biosynthetic process
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0003934	molecular_function	GTP cyclohydrolase I activity
G	0005525	molecular_function	GTP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006729	biological_process	tetrahydrobiopterin biosynthetic process
G	0006730	biological_process	one-carbon metabolic process
G	0008270	molecular_function	zinc ion binding
G	0008616	biological_process	tRNA queuosine(34) biosynthetic process
G	0016787	molecular_function	hydrolase activity
G	0032991	cellular_component	protein-containing complex
G	0042802	molecular_function	identical protein binding
G	0046654	biological_process	tetrahydrofolate biosynthetic process
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0003934	molecular_function	GTP cyclohydrolase I activity
H	0005525	molecular_function	GTP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006729	biological_process	tetrahydrobiopterin biosynthetic process
H	0006730	biological_process	one-carbon metabolic process
H	0008270	molecular_function	zinc ion binding
H	0008616	biological_process	tRNA queuosine(34) biosynthetic process
H	0016787	molecular_function	hydrolase activity
H	0032991	cellular_component	protein-containing complex
H	0042802	molecular_function	identical protein binding
H	0046654	biological_process	tetrahydrofolate biosynthetic process
H	0046872	molecular_function	metal ion binding
I	0000166	molecular_function	nucleotide binding
I	0003824	molecular_function	catalytic activity
I	0003934	molecular_function	GTP cyclohydrolase I activity
I	0005525	molecular_function	GTP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006729	biological_process	tetrahydrobiopterin biosynthetic process
I	0006730	biological_process	one-carbon metabolic process
I	0008270	molecular_function	zinc ion binding
I	0008616	biological_process	tRNA queuosine(34) biosynthetic process
I	0016787	molecular_function	hydrolase activity
I	0032991	cellular_component	protein-containing complex
I	0042802	molecular_function	identical protein binding
I	0046654	biological_process	tetrahydrofolate biosynthetic process
I	0046872	molecular_function	metal ion binding
J	0000166	molecular_function	nucleotide binding
J	0003824	molecular_function	catalytic activity
J	0003934	molecular_function	GTP cyclohydrolase I activity
J	0005525	molecular_function	GTP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006729	biological_process	tetrahydrobiopterin biosynthetic process
J	0006730	biological_process	one-carbon metabolic process
J	0008270	molecular_function	zinc ion binding
J	0008616	biological_process	tRNA queuosine(34) biosynthetic process
J	0016787	molecular_function	hydrolase activity
J	0032991	cellular_component	protein-containing complex
J	0042802	molecular_function	identical protein binding
J	0046654	biological_process	tetrahydrofolate biosynthetic process
J	0046872	molecular_function	metal ion binding
K	0000166	molecular_function	nucleotide binding
K	0003824	molecular_function	catalytic activity
K	0003934	molecular_function	GTP cyclohydrolase I activity
K	0005525	molecular_function	GTP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006729	biological_process	tetrahydrobiopterin biosynthetic process
K	0006730	biological_process	one-carbon metabolic process
K	0008270	molecular_function	zinc ion binding
K	0008616	biological_process	tRNA queuosine(34) biosynthetic process
K	0016787	molecular_function	hydrolase activity
K	0032991	cellular_component	protein-containing complex
K	0042802	molecular_function	identical protein binding
K	0046654	biological_process	tetrahydrofolate biosynthetic process
K	0046872	molecular_function	metal ion binding
L	0000166	molecular_function	nucleotide binding
L	0003824	molecular_function	catalytic activity
L	0003934	molecular_function	GTP cyclohydrolase I activity
L	0005525	molecular_function	GTP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006729	biological_process	tetrahydrobiopterin biosynthetic process
L	0006730	biological_process	one-carbon metabolic process
L	0008270	molecular_function	zinc ion binding
L	0008616	biological_process	tRNA queuosine(34) biosynthetic process
L	0016787	molecular_function	hydrolase activity
L	0032991	cellular_component	protein-containing complex
L	0042802	molecular_function	identical protein binding
L	0046654	biological_process	tetrahydrofolate biosynthetic process
L	0046872	molecular_function	metal ion binding
M	0000166	molecular_function	nucleotide binding
M	0003824	molecular_function	catalytic activity
M	0003934	molecular_function	GTP cyclohydrolase I activity
M	0005525	molecular_function	GTP binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006729	biological_process	tetrahydrobiopterin biosynthetic process
M	0006730	biological_process	one-carbon metabolic process
M	0008270	molecular_function	zinc ion binding
M	0008616	biological_process	tRNA queuosine(34) biosynthetic process
M	0016787	molecular_function	hydrolase activity
M	0032991	cellular_component	protein-containing complex
M	0042802	molecular_function	identical protein binding
M	0046654	biological_process	tetrahydrofolate biosynthetic process
M	0046872	molecular_function	metal ion binding
N	0000166	molecular_function	nucleotide binding
N	0003824	molecular_function	catalytic activity
N	0003934	molecular_function	GTP cyclohydrolase I activity
N	0005525	molecular_function	GTP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006729	biological_process	tetrahydrobiopterin biosynthetic process
N	0006730	biological_process	one-carbon metabolic process
N	0008270	molecular_function	zinc ion binding
N	0008616	biological_process	tRNA queuosine(34) biosynthetic process
N	0016787	molecular_function	hydrolase activity
N	0032991	cellular_component	protein-containing complex
N	0042802	molecular_function	identical protein binding
N	0046654	biological_process	tetrahydrofolate biosynthetic process
N	0046872	molecular_function	metal ion binding
O	0000166	molecular_function	nucleotide binding
O	0003824	molecular_function	catalytic activity
O	0003934	molecular_function	GTP cyclohydrolase I activity
O	0005525	molecular_function	GTP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006729	biological_process	tetrahydrobiopterin biosynthetic process
O	0006730	biological_process	one-carbon metabolic process
O	0008270	molecular_function	zinc ion binding
O	0008616	biological_process	tRNA queuosine(34) biosynthetic process
O	0016787	molecular_function	hydrolase activity
O	0032991	cellular_component	protein-containing complex
O	0042802	molecular_function	identical protein binding
O	0046654	biological_process	tetrahydrofolate biosynthetic process
O	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP A 401

Chain	Residue
A	HIS112
B	VAL131
B	ILE132
B	GLY133
B	LEU134
B	SER135
B	LYS136
B	ARG139
D	ARG65
D	LYS68
A	HIS113
A	VAL150
A	GLN151
A	GLU152
A	HIS179
A	CYS181
A	ARG185
B	THR87

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP B 402

Chain	Residue
B	HIS112
B	HIS113
B	VAL150
B	GLN151
B	GLU152
B	HIS179
B	ARG185
C	ARG65
C	LYS68
C	THR87
C	VAL131
C	ILE132
C	GLY133
C	LEU134
C	SER135
C	LYS136
C	ARG139

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP C 403

Chain	Residue
B	ARG65
B	LYS68
C	HIS112
C	HIS113
C	VAL150
C	GLN151
C	GLU152
C	HIS179
C	CYS181
C	ARG185
D	THR87
D	VAL131
D	ILE132
D	GLY133
D	LEU134
D	SER135
D	LYS136
D	ARG139

site_id	AC4
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP D 404

Chain	Residue
A	ARG65
A	LYS68
D	HIS112
D	HIS113
D	VAL150
D	GLN151
D	GLU152
D	HIS179
D	CYS181
D	ARG185
E	THR87
E	VAL131
E	ILE132
E	GLY133
E	LEU134
E	SER135
E	LYS136
E	ARG139

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP E 405

Chain	Residue
A	THR87
A	VAL131
A	ILE132
A	GLY133
A	LEU134
A	SER135
A	LYS136
A	ARG139
E	ARG65
E	LYS68
E	HIS112
E	HIS113
E	VAL150
E	GLN151
E	GLU152
E	HIS179
E	ARG185

site_id	AC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP F 406

Chain	Residue
G	GLY133
G	LEU134
G	SER135
G	LYS136
G	ARG139
O	ARG65
O	LYS68
F	HIS112
F	HIS113
F	VAL150
F	GLN151
F	GLU152
F	HIS179
F	CYS181
F	ARG185
G	THR87
G	VAL131
G	ILE132

site_id	AC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP G 407

Chain	Residue
G	HIS112
G	HIS113
G	VAL150
G	GLN151
G	GLU152
G	HIS179
G	ARG185
H	THR87
H	VAL131
H	ILE132
H	GLY133
H	LEU134
H	SER135
H	LYS136
H	ARG139
N	ARG65
N	LYS68

site_id	AC8
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP H 408

Chain	Residue
H	HIS112
H	HIS113
H	VAL150
H	GLN151
H	GLU152
H	HIS179
H	CYS181
H	ARG185
I	THR87
I	VAL131
I	ILE132
I	GLY133
I	LEU134
I	SER135
I	LYS136
I	ARG139
M	ARG65
M	LYS68

site_id	AC9
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP I 409

Chain	Residue
I	HIS112
I	HIS113
I	VAL150
I	GLN151
I	GLU152
I	HIS179
I	CYS181
I	ARG185
J	THR87
J	VAL131
J	ILE132
J	GLY133
J	LEU134
J	SER135
J	LYS136
J	ARG139
L	ARG65
L	LYS68

site_id	BC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP J 410

Chain	Residue
F	THR87
F	VAL131
F	ILE132
F	GLY133
F	LEU134
F	SER135
F	LYS136
F	ARG139
J	HIS112
J	HIS113
J	VAL150
J	GLN151
J	GLU152
J	HIS179
J	ARG185
K	ARG65
K	LYS68

site_id	BC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP K 411

Chain	Residue
J	ARG65
J	LYS68
K	HIS112
K	HIS113
K	VAL150
K	GLN151
K	GLU152
K	HIS179
K	ARG185
L	THR87
L	VAL131
L	ILE132
L	GLY133
L	LEU134
L	SER135
L	LYS136
L	ARG139

site_id	BC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP L 412

Chain	Residue
I	ARG65
I	LYS68
L	HIS112
L	HIS113
L	VAL150
L	GLN151
L	GLU152
L	HIS179
L	ARG185
M	THR87
M	VAL131
M	ILE132
M	GLY133
M	LEU134
M	SER135
M	LYS136
M	ARG139

site_id	BC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP M 413

Chain	Residue
H	ARG65
H	LYS68
M	HIS112
M	HIS113
M	VAL150
M	GLN151
M	GLU152
M	HIS179
M	ARG185
N	THR87
N	VAL131
N	ILE132
N	GLY133
N	LEU134
N	SER135
N	LYS136
N	ARG139

site_id	BC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTP N 414

Chain	Residue
G	ARG65
G	LYS68
N	HIS112
N	HIS113
N	VAL150
N	GLN151
N	GLU152
N	HIS179
N	ARG185
O	THR87
O	VAL131
O	ILE132
O	GLY133
O	LEU134
O	SER135
O	LYS136
O	ARG139

site_id	BC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP O 415

Chain	Residue
F	ARG65
F	LYS68
K	THR87
K	VAL131
K	ILE132
K	GLY133
K	LEU134
K	SER135
K	LYS136
K	ARG139
O	HIS112
O	HIS113
O	VAL150
O	GLN151
O	GLU152
O	HIS179
O	CYS181
O	ARG185

Functional Information from PROSITE/UniProt

site_id	PS00860
Number of Residues	11
Details	GTP_CYCLOHYDROL_1_2 GTP cyclohydrolase I signature 2. AqRpQVQERLT

Chain	Residue	Details
A	ALA145-THR155

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Binding site: {}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
A	HIS179
A	HIS112

site_id	CSA10
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
J	HIS179
J	HIS112

site_id	CSA11
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
K	HIS179
K	HIS112

site_id	CSA12
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
L	HIS179
L	HIS112

site_id	CSA13
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
M	HIS179
M	HIS112

site_id	CSA14
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
N	HIS179
N	HIS112

site_id	CSA15
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
O	HIS179
O	HIS112

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
B	HIS179
B	HIS112

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
C	HIS179
C	HIS112

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
D	HIS179
D	HIS112

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
E	HIS179
E	HIS112

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
F	HIS179
F	HIS112

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
G	HIS179
G	HIS112

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
H	HIS179
H	HIS112

site_id	CSA9
Number of Residues	2
Details	Annotated By Reference To The Literature 1gtp

Chain	Residue	Details
I	HIS179
I	HIS112

site_id	MCSA1
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
A	SER110	metal ligand
A	GLU111	electrostatic stabiliser, hydrogen bond acceptor
A	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	HIS113	metal ligand
A	GLN151	electrostatic stabiliser, hydrogen bond acceptor
A	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	CYS181	metal ligand

site_id	MCSA10
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
J	SER110	metal ligand
J	GLU111	electrostatic stabiliser, hydrogen bond acceptor
J	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
J	HIS113	metal ligand
J	GLN151	electrostatic stabiliser, hydrogen bond acceptor
J	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
J	CYS181	metal ligand

site_id	MCSA11
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
K	SER110	metal ligand
K	GLU111	electrostatic stabiliser, hydrogen bond acceptor
K	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
K	HIS113	metal ligand
K	GLN151	electrostatic stabiliser, hydrogen bond acceptor
K	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
K	CYS181	metal ligand

site_id	MCSA12
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
L	SER110	metal ligand
L	GLU111	electrostatic stabiliser, hydrogen bond acceptor
L	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
L	HIS113	metal ligand
L	GLN151	electrostatic stabiliser, hydrogen bond acceptor
L	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
L	CYS181	metal ligand

site_id	MCSA13
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
M	SER110	metal ligand
M	GLU111	electrostatic stabiliser, hydrogen bond acceptor
M	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
M	HIS113	metal ligand
M	GLN151	electrostatic stabiliser, hydrogen bond acceptor
M	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
M	CYS181	metal ligand

site_id	MCSA14
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
N	SER110	metal ligand
N	GLU111	electrostatic stabiliser, hydrogen bond acceptor
N	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
N	HIS113	metal ligand
N	GLN151	electrostatic stabiliser, hydrogen bond acceptor
N	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
N	CYS181	metal ligand

site_id	MCSA15
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
O	SER110	metal ligand
O	GLU111	electrostatic stabiliser, hydrogen bond acceptor
O	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
O	HIS113	metal ligand
O	GLN151	electrostatic stabiliser, hydrogen bond acceptor
O	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
O	CYS181	metal ligand

site_id	MCSA2
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
B	SER110	metal ligand
B	GLU111	electrostatic stabiliser, hydrogen bond acceptor
B	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
B	HIS113	metal ligand
B	GLN151	electrostatic stabiliser, hydrogen bond acceptor
B	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
B	CYS181	metal ligand

site_id	MCSA3
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
C	SER110	metal ligand
C	GLU111	electrostatic stabiliser, hydrogen bond acceptor
C	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	HIS113	metal ligand
C	GLN151	electrostatic stabiliser, hydrogen bond acceptor
C	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	CYS181	metal ligand

site_id	MCSA4
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
D	SER110	metal ligand
D	GLU111	electrostatic stabiliser, hydrogen bond acceptor
D	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
D	HIS113	metal ligand
D	GLN151	electrostatic stabiliser, hydrogen bond acceptor
D	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
D	CYS181	metal ligand

site_id	MCSA5
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
E	SER110	metal ligand
E	GLU111	electrostatic stabiliser, hydrogen bond acceptor
E	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
E	HIS113	metal ligand
E	GLN151	electrostatic stabiliser, hydrogen bond acceptor
E	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
E	CYS181	metal ligand

site_id	MCSA6
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
F	SER110	metal ligand
F	GLU111	electrostatic stabiliser, hydrogen bond acceptor
F	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
F	HIS113	metal ligand
F	GLN151	electrostatic stabiliser, hydrogen bond acceptor
F	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
F	CYS181	metal ligand

site_id	MCSA7
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
G	SER110	metal ligand
G	GLU111	electrostatic stabiliser, hydrogen bond acceptor
G	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
G	HIS113	metal ligand
G	GLN151	electrostatic stabiliser, hydrogen bond acceptor
G	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
G	CYS181	metal ligand

site_id	MCSA8
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
H	SER110	metal ligand
H	GLU111	electrostatic stabiliser, hydrogen bond acceptor
H	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
H	HIS113	metal ligand
H	GLN151	electrostatic stabiliser, hydrogen bond acceptor
H	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
H	CYS181	metal ligand

site_id	MCSA9
Number of Residues	7
Details	M-CSA 38

Chain	Residue	Details
I	SER110	metal ligand
I	GLU111	electrostatic stabiliser, hydrogen bond acceptor
I	HIS112	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
I	HIS113	metal ligand
I	GLN151	electrostatic stabiliser, hydrogen bond acceptor
I	HIS179	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
I	CYS181	metal ligand

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)