Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019853 | biological_process | L-ascorbic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NDP A 300 |
| Chain | Residue |
| A | GLY20 |
| A | VAL21 |
| A | PHE22 |
| A | ASP45 |
| A | TYR50 |
| A | LYS75 |
| A | HIS108 |
| A | SER139 |
| A | ASN140 |
| A | GLN161 |
| A | TRP187 |
| A | GLY188 |
| A | PRO189 |
| A | LEU190 |
| A | GLY191 |
| A | GLN192 |
| A | ALA215 |
| A | PHE230 |
| A | PRO231 |
| A | LYS232 |
| A | SER233 |
| A | VAL234 |
| A | ARG235 |
| A | ARG238 |
| A | GLU241 |
| A | ASN242 |
| A | HOH332 |
| A | HOH342 |
| A | HOH352 |
| A | HOH396 |
| A | HOH406 |
| site_id | CIC |
| Number of Residues | 9 |
| Details | THE RESIDUE LINE THE ACTIVE SITE OF THE ENZYME. |
| Chain | Residue |
| A | PHE22 |
| A | ASP45 |
| A | ALA47 |
| A | TYR50 |
| A | LYS75 |
| A | LEU106 |
| A | SER139 |
| A | ASN140 |
| A | TRP187 |
Functional Information from PROSITE/UniProt
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRHIDTAaiygnEegVG |
| Chain | Residue | Details |
| A | GLY40-GLY57 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"11399090","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11399090","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 54 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14718658","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | LYS75 | |
| A | ASP45 | |
| A | TYR50 | |
| A | HIS108 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | LYS75 | |
| A | TYR50 | |
