1A52
ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED TO ESTRADIOL
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EST A 1 |
| Chain | Residue |
| A | GLU353 |
| A | LEU387 |
| A | LEU391 |
| A | ARG394 |
| A | HIS524 |
| A | LEU525 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EST B 2 |
| Chain | Residue |
| B | LEU391 |
| B | ARG394 |
| B | HIS524 |
| B | LEU525 |
| B | LEU346 |
| B | GLU353 |
| B | LEU387 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE AU A 2 |
| Chain | Residue |
| A | TYR459 |
| A | HIS476 |
| B | ARG434 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE AU A 3 |
| Chain | Residue |
| A | CYS381 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE AU A 5 |
| Chain | Residue |
| A | PHE337 |
| A | CYS417 |
| A | HOH562 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE AU B 12 |
| Chain | Residue |
| A | ARG434 |
| B | HIS476 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE AU B 13 |
| Chain | Residue |
| A | HIS516 |
| B | CYS381 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE AU B 15 |
| Chain | Residue |
| B | HOH39 |
| B | HOH40 |
| B | CYS417 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9338790","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9600906","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ERE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by Tyr-kinases","evidences":[{"source":"PubMed","id":"7539106","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
