1A4U
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006066 | biological_process | alcohol metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006066 | biological_process | alcohol metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | ACA |
| Number of Residues | 3 |
| Details | ACTIVE SITE, CATALYTIC TRIAD. |
| Chain | Residue |
| A | SER138 |
| A | TYR151 |
| A | LYS155 |
| site_id | ACB |
| Number of Residues | 3 |
| Details | ACTIVE SITE, CATALYTIC TRIAD. |
| Chain | Residue |
| B | LYS155 |
| B | SER138 |
| B | TYR151 |
| site_id | NAD |
| Number of Residues | 1 |
| Details | NAD/NADP SELECTIVITY AMINO ACID. |
| Chain | Residue |
| A | ASP37 |
| site_id | ND' |
| Number of Residues | 1 |
| Details | NAD/NADP SELECTIVITY AMINO ACID. |
| Chain | Residue |
| B | ASP37 |
| site_id | NDA |
| Number of Residues | 3 |
| Details | NAD BINDING MOTIF. |
| Chain | Residue |
| A | ALA13 |
| A | GLY15 |
| A | GLY18 |
| site_id | NDB |
| Number of Residues | 3 |
| Details | NAD BINDING MOTIF. |
| Chain | Residue |
| B | ALA13 |
| B | GLY15 |
| B | GLY18 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvtgfnaihqVpvYSASKAAVvSFTnSLA |
| Chain | Residue | Details |
| A | SER138-ALA166 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | TYR151 | |
| B | TYR151 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10366509 |
| Chain | Residue | Details |
| B | PHE10 | |
| A | PHE10 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | SER138 | |
| B | SER138 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000269|PubMed:2707261 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 |
