1A4O
14-3-3 PROTEIN ZETA ISOFORM
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007165 | biological_process | signal transduction |
| A | 0008104 | biological_process | protein localization |
| A | 0042470 | cellular_component | melanosome |
| A | 0050815 | molecular_function | phosphoserine residue binding |
| A | 0070372 | biological_process | regulation of ERK1 and ERK2 cascade |
| A | 0140311 | molecular_function | protein sequestering activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0007165 | biological_process | signal transduction |
| B | 0008104 | biological_process | protein localization |
| B | 0042470 | cellular_component | melanosome |
| B | 0050815 | molecular_function | phosphoserine residue binding |
| B | 0070372 | biological_process | regulation of ERK1 and ERK2 cascade |
| B | 0140311 | molecular_function | protein sequestering activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006468 | biological_process | protein phosphorylation |
| C | 0007165 | biological_process | signal transduction |
| C | 0008104 | biological_process | protein localization |
| C | 0042470 | cellular_component | melanosome |
| C | 0050815 | molecular_function | phosphoserine residue binding |
| C | 0070372 | biological_process | regulation of ERK1 and ERK2 cascade |
| C | 0140311 | molecular_function | protein sequestering activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006468 | biological_process | protein phosphorylation |
| D | 0007165 | biological_process | signal transduction |
| D | 0008104 | biological_process | protein localization |
| D | 0042470 | cellular_component | melanosome |
| D | 0050815 | molecular_function | phosphoserine residue binding |
| D | 0070372 | biological_process | regulation of ERK1 and ERK2 cascade |
| D | 0140311 | molecular_function | protein sequestering activity |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | SITE: Interaction with phosphoserine on interacting protein => ECO:0000269|PubMed:18550856, ECO:0000269|PubMed:9632691 |
| Chain | Residue | Details |
| A | ARG56 | |
| A | ARG127 | |
| B | ARG56 | |
| B | ARG127 | |
| C | ARG56 | |
| C | ARG127 | |
| D | ARG56 | |
| D | ARG127 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P63104 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 | |
| C | MET1 | |
| D | MET1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P63104 |
| Chain | Residue | Details |
| A | LYS3 | |
| A | LYS68 | |
| B | LYS3 | |
| B | LYS68 | |
| C | LYS3 | |
| C | LYS68 | |
| D | LYS3 | |
| D | LYS68 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000250|UniProtKB:P63104 |
| Chain | Residue | Details |
| A | SER58 | |
| B | SER58 | |
| C | SER58 | |
| D | SER58 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63104 |
| Chain | Residue | Details |
| A | SER184 | |
| A | SER207 | |
| B | SER184 | |
| B | SER207 | |
| C | SER184 | |
| C | SER207 | |
| D | SER184 | |
| D | SER207 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63102 |
| Chain | Residue | Details |
| A | SER210 | |
| B | SER210 | |
| C | SER210 | |
| D | SER210 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by CK1 => ECO:0000250|UniProtKB:P63104 |
| Chain | Residue | Details |
| A | THR232 | |
| B | THR232 | |
| C | THR232 | |
| D | THR232 |
