1A4K

DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002250	biological_process	adaptive immune response
A	0003823	molecular_function	antigen binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006955	biological_process	immune response
A	0016064	biological_process	immunoglobulin mediated immune response
A	0019814	cellular_component	immunoglobulin complex
A	0050853	biological_process	B cell receptor signaling pathway
A	0070062	cellular_component	extracellular exosome
A	0071735	cellular_component	IgG immunoglobulin complex
A	0071738	cellular_component	IgD immunoglobulin complex
A	0071742	cellular_component	IgE immunoglobulin complex
A	0071745	cellular_component	IgA immunoglobulin complex
A	0071753	cellular_component	IgM immunoglobulin complex
A	0072562	cellular_component	blood microparticle
L	0002250	biological_process	adaptive immune response
L	0003823	molecular_function	antigen binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005886	cellular_component	plasma membrane
L	0006955	biological_process	immune response
L	0016064	biological_process	immunoglobulin mediated immune response
L	0019814	cellular_component	immunoglobulin complex
L	0050853	biological_process	B cell receptor signaling pathway
L	0070062	cellular_component	extracellular exosome
L	0071735	cellular_component	IgG immunoglobulin complex
L	0071738	cellular_component	IgD immunoglobulin complex
L	0071742	cellular_component	IgE immunoglobulin complex
L	0071745	cellular_component	IgA immunoglobulin complex
L	0071753	cellular_component	IgM immunoglobulin complex
L	0072562	cellular_component	blood microparticle

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD L 5028

Chain	Residue
L	GLU79
L	GLU81
L	HIS93
L	HOH5037
L	HOH5038
L	HOH5039

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 5028

Chain	Residue
A	HOH5051
A	HOH5055
A	HOH5062
A	GLU79
A	GLU81
A	HIS93

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD L 5029

Chain	Residue
H	HIS164
L	ASN138
L	HOH5049
L	HOH5057

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 5029

Chain	Residue
A	ASN138
A	HOH5059
A	HOH5061
A	HOH5071
B	HIS164

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FRA B 3083

Chain	Residue
B	ASN31
B	GLY33
B	ASN35
B	ALA95
B	GLU96
B	ARG97
B	ARG100
H	TYR53

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FRA H 3083

Chain	Residue
B	TYR53
H	ASN31
H	GLY33
H	ASN35
H	TRP50
H	ALA95
H	ARG97
H	ARG100
H	HOH3114
H	HOH3127

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR194-HIS200

---