1A3G

BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE FROM ESCHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
A	0005829	cellular_component	cytosol
A	0006532	biological_process	L-aspartate biosynthetic process
A	0009081	biological_process	branched-chain amino acid metabolic process
A	0009098	biological_process	L-leucine biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0042802	molecular_function	identical protein binding
A	0046394	biological_process	carboxylic acid biosynthetic process
A	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
A	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
A	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity
B	0003824	molecular_function	catalytic activity
B	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
B	0005829	cellular_component	cytosol
B	0006532	biological_process	L-aspartate biosynthetic process
B	0009081	biological_process	branched-chain amino acid metabolic process
B	0009098	biological_process	L-leucine biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0042802	molecular_function	identical protein binding
B	0046394	biological_process	carboxylic acid biosynthetic process
B	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
B	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
B	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity
C	0003824	molecular_function	catalytic activity
C	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
C	0005829	cellular_component	cytosol
C	0006532	biological_process	L-aspartate biosynthetic process
C	0009081	biological_process	branched-chain amino acid metabolic process
C	0009098	biological_process	L-leucine biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0042802	molecular_function	identical protein binding
C	0046394	biological_process	carboxylic acid biosynthetic process
C	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
C	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
C	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PLP A 413

Chain	Residue
A	ARG59
A	THR257
A	HOH1598
A	HOH1615
A	LYS159
A	TYR164
A	GLU193
A	GLY196
A	GLU197
A	GLY219
A	ILE220
A	THR221

---

site_id	AC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PLP B 413

Chain	Residue
B	ARG59
B	LYS159
B	TYR164
B	GLU193
B	GLY196
B	GLU197
B	ASN198
B	LEU217
B	GLY219
B	ILE220
B	THR221
B	THR257
B	HOH1533
B	HOH1577

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PLP C 413

Chain	Residue
C	ARG59
C	LYS159
C	TYR164
C	GLU193
C	GLY196
C	GLU197
C	GLY219
C	ILE220
C	THR221
C	THR257
C	HOH1538
C	HOH1592

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Functional Information from PROSITE/UniProt

site_id	PS00770
Number of Residues	30
Details	AA_TRANSFER_CLASS_4 Aminotransferases class-IV signature. EgAgeNLFevkdgv......LfTppftssa.LpGItR

Chain	Residue	Details
A	GLU193-ARG222

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1iyd

Chain	Residue	Details
A	LYS159

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1iyd

Chain	Residue	Details
B	LYS159

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site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1iyd

Chain	Residue	Details
C	LYS159

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site_id	MCSA1
Number of Residues	1
Details	M-CSA 813

Chain	Residue	Details
A	LYS159	proton shuttle (general acid/base)

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site_id	MCSA2
Number of Residues	1
Details	M-CSA 813

Chain	Residue	Details
B	LYS159	proton shuttle (general acid/base)

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site_id	MCSA3
Number of Residues	1
Details	M-CSA 813

Chain	Residue	Details
C	LYS159	proton shuttle (general acid/base)

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