1A0M
1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NH2 A 17 |
| Chain | Residue |
| A | PRO13 |
| A | CYS16 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NH2 B 17 |
| Chain | Residue |
| B | PRO13 |
| B | CYS16 |
| A | HOH21 |
| B | HOH27 |
Functional Information from PROSITE/UniProt
| site_id | PS60014 |
| Number of Residues | 15 |
| Details | ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCSdPRCNmnnpDYC |
| Chain | Residue | Details |
| A | CYS2-CYS16 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Peptide: {"description":"Alpha-conotoxin EpI","featureId":"PRO_0000044457","evidences":[{"source":"PubMed","id":"9624161","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Region: {"description":"Ser-Xaa-Pro motif, crucial for potent interaction with nAChR","evidences":[{"source":"UniProtKB","id":"P56636","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Sulfotyrosine","evidences":[{"source":"PubMed","id":"9624161","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Cysteine amide","evidences":[{"source":"PubMed","id":"9624161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9708977","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
