168L
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0044659 | biological_process | viral release from host cell by cytolysis |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0044659 | biological_process | viral release from host cell by cytolysis |
| C | 0003796 | molecular_function | lysozyme activity |
| C | 0009253 | biological_process | peptidoglycan catabolic process |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0016998 | biological_process | cell wall macromolecule catabolic process |
| C | 0030430 | cellular_component | host cell cytoplasm |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0042742 | biological_process | defense response to bacterium |
| C | 0044659 | biological_process | viral release from host cell by cytolysis |
| D | 0003796 | molecular_function | lysozyme activity |
| D | 0009253 | biological_process | peptidoglycan catabolic process |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0016998 | biological_process | cell wall macromolecule catabolic process |
| D | 0030430 | cellular_component | host cell cytoplasm |
| D | 0031640 | biological_process | killing of cells of another organism |
| D | 0042742 | biological_process | defense response to bacterium |
| D | 0044659 | biological_process | viral release from host cell by cytolysis |
| E | 0003796 | molecular_function | lysozyme activity |
| E | 0009253 | biological_process | peptidoglycan catabolic process |
| E | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| E | 0016998 | biological_process | cell wall macromolecule catabolic process |
| E | 0030430 | cellular_component | host cell cytoplasm |
| E | 0031640 | biological_process | killing of cells of another organism |
| E | 0042742 | biological_process | defense response to bacterium |
| E | 0044659 | biological_process | viral release from host cell by cytolysis |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | GLU11 | |
| B | GLU11 | |
| C | GLU11 | |
| D | GLU11 | |
| E | GLU11 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | ASP20 | |
| B | ASP20 | |
| C | ASP20 | |
| D | ASP20 | |
| E | ASP20 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | LEU32 | |
| E | PHE104 | |
| A | PHE104 | |
| B | LEU32 | |
| B | PHE104 | |
| C | LEU32 | |
| C | PHE104 | |
| D | LEU32 | |
| D | PHE104 | |
| E | LEU32 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000303|PubMed:7831309 |
| Chain | Residue | Details |
| A | SER117 | |
| E | ALA132 | |
| A | ALA132 | |
| B | SER117 | |
| B | ALA132 | |
| C | SER117 | |
| C | ALA132 | |
| D | SER117 | |
| D | ALA132 | |
| E | SER117 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| A | GLU11 | |
| A | ASP20 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| B | GLU11 | |
| B | ASP20 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| C | GLU11 | |
| C | ASP20 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| D | GLU11 | |
| D | ASP20 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| E | GLU11 | |
| E | ASP20 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| A | GLU11 | proton shuttle (general acid/base) |
| A | ASP20 | covalent catalysis |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| B | GLU11 | proton shuttle (general acid/base) |
| B | ASP20 | covalent catalysis |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| C | GLU11 | proton shuttle (general acid/base) |
| C | ASP20 | covalent catalysis |
| site_id | MCSA4 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| D | GLU11 | proton shuttle (general acid/base) |
| D | ASP20 | covalent catalysis |
| site_id | MCSA5 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| E | GLU11 | proton shuttle (general acid/base) |
| E | ASP20 | covalent catalysis |
