13ES
Cryo-EM structure of HAdV-C5 hexon trimer in complex with human coagulation factor X (FX)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005198 | molecular_function | structural molecule activity |
| A | 0019028 | cellular_component | viral capsid |
| A | 0039623 | cellular_component | T=25 icosahedral viral capsid |
| A | 0042025 | cellular_component | host cell nucleus |
| A | 0043657 | cellular_component | host cell |
| A | 0046718 | biological_process | symbiont entry into host cell |
| A | 0075521 | biological_process | microtubule-dependent intracellular transport of viral material towards nucleus |
| A | 0075606 | biological_process | transport of viral material towards nucleus |
| B | 0005198 | molecular_function | structural molecule activity |
| B | 0019028 | cellular_component | viral capsid |
| B | 0039623 | cellular_component | T=25 icosahedral viral capsid |
| B | 0042025 | cellular_component | host cell nucleus |
| B | 0043657 | cellular_component | host cell |
| B | 0046718 | biological_process | symbiont entry into host cell |
| B | 0075521 | biological_process | microtubule-dependent intracellular transport of viral material towards nucleus |
| B | 0075606 | biological_process | transport of viral material towards nucleus |
| C | 0005198 | molecular_function | structural molecule activity |
| C | 0019028 | cellular_component | viral capsid |
| C | 0039623 | cellular_component | T=25 icosahedral viral capsid |
| C | 0042025 | cellular_component | host cell nucleus |
| C | 0043657 | cellular_component | host cell |
| C | 0046718 | biological_process | symbiont entry into host cell |
| C | 0075521 | biological_process | microtubule-dependent intracellular transport of viral material towards nucleus |
| C | 0075606 | biological_process | transport of viral material towards nucleus |
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDglgeYtCtC |
| Chain | Residue | Details |
| G | CYS61-CYS72 |
| site_id | PS00011 |
| Number of Residues | 26 |
| Details | GLA_1 Vitamin K-dependent carboxylation domain. EcmEEtCsyeearEvfedsdktne.FW |
| Chain | Residue | Details |
| G | CGU16-TRP41 |
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CtCleGfeGKnC |
| Chain | Residue | Details |
| G | CYS70-CYS81 |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| G | LEU232-CYS237 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPHV |
| Chain | Residue | Details |
| G | ASP373-VAL384 |
| site_id | PS01186 |
| Number of Residues | 12 |
| Details | EGF_2 EGF-like domain signature 2. CtCleGFegkn....C |
| Chain | Residue | Details |
| G | CYS70-CYS81 | |
| G | CYS109-CYS124 |
| site_id | PS01187 |
| Number of Residues | 25 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DgDQCetsp..........Cqnqgk..CkDglgeYtC |
| Chain | Residue | Details |
| G | ASP46-CYS70 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Site: {"description":"Involved in interaction with pre-protein VI","evidences":[{"source":"HAMAP-Rule","id":"MF_04051","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04051","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphotyrosine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04051","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"4-carboxyglutamate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00463","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"6871167","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
