13BS

CryoEM structure of IL36RA-Fab complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001960	biological_process	negative regulation of cytokine-mediated signaling pathway
A	0005152	molecular_function	interleukin-1 receptor antagonist activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0007165	biological_process	signal transduction
A	0019732	biological_process	antifungal humoral response
A	0032689	biological_process	negative regulation of type II interferon production
A	0032700	biological_process	negative regulation of interleukin-17 production
A	0071222	biological_process	cellular response to lipopolysaccharide

Functional Information from PROSITE/UniProt

site_id	PS00253
Number of Residues	21
Details	INTERLEUKIN_1 Interleukin-1 signature. FeSAayPgwFLCTvpeadqpV

Chain	Residue	Details
A	PHE111-VAL131

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site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR199-HIS205
L	TYR192-HIS198

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