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12ES

Cryo-EM structure of BCMA in complex with the BCMA-targeted Fab arm of linvoseltamab and the Fab fragment of an anti-kappa light chain antibody REGN654

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
BTYR192-HIS198
ETYR193-HIS199
DTYR206-HIS212

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues34
DetailsRepeat: {"description":"TNFR-Cys"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsSite: {"description":"Breakpoint for translocation to form IL2/TNFRSF17 oncogene"}
ChainResidueDetails

258222

PDB entries from 2026-08-19

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