10ZZ

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP*

Functional Information from GO Data

Chain	GOid	namespace	contents
b	0000027	biological_process	ribosomal large subunit assembly
b	0000464	biological_process	endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
b	0000465	biological_process	exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005730	cellular_component	nucleolus
b	0008097	molecular_function	5S rRNA binding
b	0019843	molecular_function	rRNA binding
b	0030687	cellular_component	preribosome, large subunit precursor
b	0042134	molecular_function	rRNA primary transcript binding
b	0042254	biological_process	ribosome biogenesis
G	0000470	biological_process	maturation of LSU-rRNA
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006364	biological_process	rRNA processing
G	0022625	cellular_component	cytosolic large ribosomal subunit
i	0000470	biological_process	maturation of LSU-rRNA
i	0002181	biological_process	cytoplasmic translation
i	0003723	molecular_function	RNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	0180023	biological_process	cytosolic large ribosomal subunit assembly
i	1990904	cellular_component	ribonucleoprotein complex
m	0000280	biological_process	nuclear division
m	0003723	molecular_function	RNA binding
m	0003729	molecular_function	mRNA binding
m	0005515	molecular_function	protein binding
m	0005730	cellular_component	nucleolus
m	0006364	biological_process	rRNA processing
m	0030687	cellular_component	preribosome, large subunit precursor
m	0034399	cellular_component	nuclear periphery
m	0042273	biological_process	ribosomal large subunit biogenesis
m	0042802	molecular_function	identical protein binding
N	0000470	biological_process	maturation of LSU-rRNA
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0180023	biological_process	cytosolic large ribosomal subunit assembly
R	0003674	molecular_function	molecular_function
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0006364	biological_process	rRNA processing
R	0031490	molecular_function	chromatin DNA binding
R	1901838	biological_process	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. AAIGtfDpQIEIWNL

Chain	Residue	Details
R	ALA230-LEU244
R	LEU302-LEU316
R	MET492-VAL506

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CkkmgVPYaiVkGKarLG

Chain	Residue	Details
G	CYS170-GLY187

---

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRlIDLIR

Chain	Residue	Details
i	PRO52-ARG62

---

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGFVIYRvRVrRG

Chain	Residue	Details
N	ASP46-GLY69

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	40
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	Repeat: {"description":"WD 3"}

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Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	38
Details	Repeat: {"description":"WD 4"}

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Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	42
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	31
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---