10JC

CCAN dimer purified from budding yeast

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000776	cellular_component	kinetochore
A	0000939	cellular_component	inner kinetochore
A	0003674	molecular_function	molecular_function
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0007059	biological_process	chromosome segregation
A	0008608	biological_process	attachment of spindle microtubules to kinetochore
A	0034087	biological_process	establishment of mitotic sister chromatid cohesion
b	0000776	cellular_component	kinetochore
b	0000939	cellular_component	inner kinetochore
b	0003674	molecular_function	molecular_function
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0007059	biological_process	chromosome segregation
b	0008150	biological_process	biological_process
b	0008608	biological_process	attachment of spindle microtubules to kinetochore
B	0000776	cellular_component	kinetochore
B	0000939	cellular_component	inner kinetochore
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0007059	biological_process	chromosome segregation
B	0008608	biological_process	attachment of spindle microtubules to kinetochore
B	0034087	biological_process	establishment of mitotic sister chromatid cohesion
c	0000776	cellular_component	kinetochore
c	0000939	cellular_component	inner kinetochore
c	0003674	molecular_function	molecular_function
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0007059	biological_process	chromosome segregation
c	0008608	biological_process	attachment of spindle microtubules to kinetochore
c	0031511	cellular_component	Mis6-Sim4 complex
C	0000776	cellular_component	kinetochore
C	0000939	cellular_component	inner kinetochore
C	0003674	molecular_function	molecular_function
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0006270	biological_process	DNA replication initiation
C	0007059	biological_process	chromosome segregation
C	0007094	biological_process	mitotic spindle assembly checkpoint signaling
C	0008608	biological_process	attachment of spindle microtubules to kinetochore
C	0034087	biological_process	establishment of mitotic sister chromatid cohesion
D	0000776	cellular_component	kinetochore
D	0000939	cellular_component	inner kinetochore
D	0003674	molecular_function	molecular_function
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0006270	biological_process	DNA replication initiation
D	0007059	biological_process	chromosome segregation
D	0007094	biological_process	mitotic spindle assembly checkpoint signaling
D	0008608	biological_process	attachment of spindle microtubules to kinetochore
D	0034087	biological_process	establishment of mitotic sister chromatid cohesion
E	0000776	cellular_component	kinetochore
E	0000939	cellular_component	inner kinetochore
E	0003674	molecular_function	molecular_function
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0007059	biological_process	chromosome segregation
E	0008608	biological_process	attachment of spindle microtubules to kinetochore
E	0034087	biological_process	establishment of mitotic sister chromatid cohesion
F	0000776	cellular_component	kinetochore
F	0000939	cellular_component	inner kinetochore
F	0003674	molecular_function	molecular_function
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0007059	biological_process	chromosome segregation
F	0008608	biological_process	attachment of spindle microtubules to kinetochore
F	0034087	biological_process	establishment of mitotic sister chromatid cohesion
G	0000776	cellular_component	kinetochore
G	0000939	cellular_component	inner kinetochore
G	0000940	cellular_component	outer kinetochore
G	0003674	molecular_function	molecular_function
G	0005634	cellular_component	nucleus
G	0007059	biological_process	chromosome segregation
G	0008608	biological_process	attachment of spindle microtubules to kinetochore
G	0030437	biological_process	ascospore formation
G	0034087	biological_process	establishment of mitotic sister chromatid cohesion
G	0034089	biological_process	establishment of meiotic sister chromatid cohesion
G	0034090	biological_process	maintenance of meiotic sister chromatid cohesion
G	0045144	biological_process	meiotic sister chromatid segregation
G	0071459	biological_process	protein localization to chromosome, centromeric region
H	0000776	cellular_component	kinetochore
H	0000939	cellular_component	inner kinetochore
H	0003674	molecular_function	molecular_function
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0007059	biological_process	chromosome segregation
H	0008608	biological_process	attachment of spindle microtubules to kinetochore
H	0034087	biological_process	establishment of mitotic sister chromatid cohesion
I	0000776	cellular_component	kinetochore
I	0000939	cellular_component	inner kinetochore
I	0003674	molecular_function	molecular_function
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0006270	biological_process	DNA replication initiation
I	0007059	biological_process	chromosome segregation
I	0007094	biological_process	mitotic spindle assembly checkpoint signaling
I	0008608	biological_process	attachment of spindle microtubules to kinetochore
I	0034087	biological_process	establishment of mitotic sister chromatid cohesion
J	0000776	cellular_component	kinetochore
J	0000939	cellular_component	inner kinetochore
J	0000940	cellular_component	outer kinetochore
J	0005198	molecular_function	structural molecule activity
J	0005634	cellular_component	nucleus
J	0007059	biological_process	chromosome segregation
J	0007094	biological_process	mitotic spindle assembly checkpoint signaling
J	0008608	biological_process	attachment of spindle microtubules to kinetochore
J	0034087	biological_process	establishment of mitotic sister chromatid cohesion
J	0034089	biological_process	establishment of meiotic sister chromatid cohesion
J	0034090	biological_process	maintenance of meiotic sister chromatid cohesion
J	0051382	biological_process	kinetochore assembly
J	0071459	biological_process	protein localization to chromosome, centromeric region
K	0000776	cellular_component	kinetochore
K	0000939	cellular_component	inner kinetochore
K	0003674	molecular_function	molecular_function
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0007059	biological_process	chromosome segregation
K	0008608	biological_process	attachment of spindle microtubules to kinetochore
K	0034087	biological_process	establishment of mitotic sister chromatid cohesion
L	0000776	cellular_component	kinetochore
L	0000939	cellular_component	inner kinetochore
L	0000940	cellular_component	outer kinetochore
L	0003674	molecular_function	molecular_function
L	0005634	cellular_component	nucleus
L	0007059	biological_process	chromosome segregation
L	0008608	biological_process	attachment of spindle microtubules to kinetochore
L	0030437	biological_process	ascospore formation
L	0034087	biological_process	establishment of mitotic sister chromatid cohesion
L	0034089	biological_process	establishment of meiotic sister chromatid cohesion
L	0034090	biological_process	maintenance of meiotic sister chromatid cohesion
L	0045144	biological_process	meiotic sister chromatid segregation
L	0071459	biological_process	protein localization to chromosome, centromeric region
M	0000776	cellular_component	kinetochore
M	0000817	cellular_component	COMA complex
M	0000939	cellular_component	inner kinetochore
M	0003674	molecular_function	molecular_function
M	0005634	cellular_component	nucleus
M	0007059	biological_process	chromosome segregation
M	0008608	biological_process	attachment of spindle microtubules to kinetochore
M	0034087	biological_process	establishment of mitotic sister chromatid cohesion
M	0071459	biological_process	protein localization to chromosome, centromeric region
M	1905262	biological_process	negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination
N	0000776	cellular_component	kinetochore
N	0000939	cellular_component	inner kinetochore
N	0000940	cellular_component	outer kinetochore
N	0005198	molecular_function	structural molecule activity
N	0005634	cellular_component	nucleus
N	0007059	biological_process	chromosome segregation
N	0007094	biological_process	mitotic spindle assembly checkpoint signaling
N	0008608	biological_process	attachment of spindle microtubules to kinetochore
N	0034087	biological_process	establishment of mitotic sister chromatid cohesion
N	0034089	biological_process	establishment of meiotic sister chromatid cohesion
N	0034090	biological_process	maintenance of meiotic sister chromatid cohesion
N	0051382	biological_process	kinetochore assembly
N	0071459	biological_process	protein localization to chromosome, centromeric region
O	0000776	cellular_component	kinetochore
O	0000817	cellular_component	COMA complex
O	0000939	cellular_component	inner kinetochore
O	0003674	molecular_function	molecular_function
O	0005634	cellular_component	nucleus
O	0007059	biological_process	chromosome segregation
O	0008608	biological_process	attachment of spindle microtubules to kinetochore
O	0034087	biological_process	establishment of mitotic sister chromatid cohesion
O	0071459	biological_process	protein localization to chromosome, centromeric region
O	1905262	biological_process	negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination
P	0000776	cellular_component	kinetochore
P	0000817	cellular_component	COMA complex
P	0000939	cellular_component	inner kinetochore
P	0003674	molecular_function	molecular_function
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0007059	biological_process	chromosome segregation
P	0007094	biological_process	mitotic spindle assembly checkpoint signaling
P	0008608	biological_process	attachment of spindle microtubules to kinetochore
P	0034087	biological_process	establishment of mitotic sister chromatid cohesion
P	0071459	biological_process	protein localization to chromosome, centromeric region
Q	0000776	cellular_component	kinetochore
Q	0000817	cellular_component	COMA complex
Q	0000939	cellular_component	inner kinetochore
Q	0003674	molecular_function	molecular_function
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0007059	biological_process	chromosome segregation
Q	0008608	biological_process	attachment of spindle microtubules to kinetochore
R	0000776	cellular_component	kinetochore
R	0000817	cellular_component	COMA complex
R	0000939	cellular_component	inner kinetochore
R	0003674	molecular_function	molecular_function
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0007059	biological_process	chromosome segregation
R	0007094	biological_process	mitotic spindle assembly checkpoint signaling
R	0008608	biological_process	attachment of spindle microtubules to kinetochore
R	0034087	biological_process	establishment of mitotic sister chromatid cohesion
R	0071459	biological_process	protein localization to chromosome, centromeric region
S	0000776	cellular_component	kinetochore
S	0000817	cellular_component	COMA complex
S	0000939	cellular_component	inner kinetochore
S	0003674	molecular_function	molecular_function
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0007059	biological_process	chromosome segregation
S	0008608	biological_process	attachment of spindle microtubules to kinetochore
T	0000776	cellular_component	kinetochore
T	0000939	cellular_component	inner kinetochore
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0007059	biological_process	chromosome segregation
T	0019237	molecular_function	centromeric DNA binding
T	0044877	molecular_function	protein-containing complex binding
T	1905560	biological_process	negative regulation of kinetochore assembly
W	0000776	cellular_component	kinetochore
W	0000939	cellular_component	inner kinetochore
W	0005634	cellular_component	nucleus
W	0007059	biological_process	chromosome segregation
W	0019237	molecular_function	centromeric DNA binding
Y	0000776	cellular_component	kinetochore
Y	0000939	cellular_component	inner kinetochore
Y	0003674	molecular_function	molecular_function
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0007059	biological_process	chromosome segregation
Y	0008150	biological_process	biological_process
Y	0008608	biological_process	attachment of spindle microtubules to kinetochore
Z	0000776	cellular_component	kinetochore
Z	0000939	cellular_component	inner kinetochore
Z	0003674	molecular_function	molecular_function
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0007059	biological_process	chromosome segregation
Z	0008608	biological_process	attachment of spindle microtubules to kinetochore
Z	0031511	cellular_component	Mis6-Sim4 complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by MPS1 and IPL1","evidences":[{"source":"PubMed","id":"22561345","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	176
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---