10EX
SK5A-Matured apo state in complex with GluN1-GluN2B, full refinement
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 112 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"P35439","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Intramembrane: {"description":"Discontinuously helical","evidences":[{"source":"UniProtKB","id":"A0A1L8F5J9","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"UniProtKB","id":"P35439","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 328 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"UniProtKB","id":"P35439","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | Region: {"description":"Pore-forming","evidences":[{"source":"UniProtKB","id":"A0A1L8F5J9","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P35439","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 30 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 108 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34321660","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EU8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 22 |
| Details | Intramembrane: {"description":"Discontinuously helical","evidences":[{"source":"PubMed","id":"34321660","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EU8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 26 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34321660","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EU8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 342 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34321660","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EU8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 38 |
| Details | Region: {"description":"Pore-forming","evidences":[{"source":"UniProtKB","id":"A7XY94","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q00960","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | Site: {"description":"Functional determinant of NMDA receptors","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"26912815","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5EWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EWM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"26912815","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34321660","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5EWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EWM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EU8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"34321660","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EU8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
