9QFL

Crystal structure of YTHDF2 in complex with compound 15 (AI-DF2-68)

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X06DA
Synchrotron site	SLS
Beamline	X06DA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2023-02-03
Detector	DECTRIS PILATUS 2M-F
Wavelength(s)	1
Spacegroup name	P 65
Unit cell lengths	79.720, 79.720, 114.430
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	39.860 - 1.700
R-factor	0.2043
Rwork	0.203
R-free	0.22270
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.006
RMSD bond angle	0.739
Data reduction software	XDS
Data scaling software	XSCALE
Phasing software	PHASER
Refinement software	PHENIX (1.21.2_5419)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	50.000	1.810
High resolution limit [Å]	1.700	1.700
Number of reflections	44845	7151
<I/σ(I)>	19.35
Completeness [%]	99.8
Redundancy	9
CC(1/2)	0.999	0.816

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		277.15	1.975 M Ammonium sulfate, 0.1 M Sodium citrate tribasic pH 5.2