9OOB
Crystal structure of MYST acetyltransferase domain in complex with inhibitor 8
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | AUSTRALIAN SYNCHROTRON BEAMLINE MX2 |
| Synchrotron site | Australian Synchrotron |
| Beamline | MX2 |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2024-07-16 |
| Detector | DECTRIS EIGER2 X 9M |
| Wavelength(s) | 0.953725305062 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 46.545, 58.623, 120.150 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 34.880 - 1.830 |
| R-factor | 0.1781 |
| Rwork | 0.177 |
| R-free | 0.20760 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.009 |
| RMSD bond angle | 0.999 |
| Data reduction software | XDS |
| Data scaling software | Aimless |
| Phasing software | PHASER |
| Refinement software | PHENIX (1.20.1_4487) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 34.880 | 1.890 |
| High resolution limit [Å] | 1.830 | 1.830 |
| Rmerge | 0.067 | 0.689 |
| Rmeas | 0.071 | 0.737 |
| Rpim | 0.025 | 0.259 |
| Number of reflections | 56088 | 2900 |
| <I/σ(I)> | 20.38 | 2.91 |
| Completeness [%] | 99.9 | 99.28 |
| Redundancy | 7.8 | 7.9 |
| CC(1/2) | 0.999 | 0.855 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 7 | 294 | 0.1 M Tris pH 7.0, 0.25 M MgCl2, 8% PEG8K |
