9HHD

Crystal Structure of the Plasmodium falciparum Bromodomain PfBDP1 in complex with RMM2

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X06SA
Synchrotron site	SLS
Beamline	X06SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2022-01-30
Detector	DECTRIS EIGER X 16M
Wavelength(s)	1.000033
Spacegroup name	I 2 2 2
Unit cell lengths	38.447, 88.106, 108.046
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	44.050 - 2.260
R-factor	0.2106
Rwork	0.208
R-free	0.24930
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.007
RMSD bond angle	0.793
Data reduction software	XDS
Data scaling software	Aimless
Phasing software	PHASER
Refinement software	PHENIX (1.21_5207)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	44.050	2.330
High resolution limit [Å]	2.260	2.260
Rmerge	0.318
Rpim		0.748
Number of reflections	8932	782
<I/σ(I)>	8.7
Completeness [%]	99.7
Redundancy	13.2
CC(1/2)	0.995	0.685

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		277	0.3 M LiSO4, 15% PEG3350, 0.1 M Tris pH 7.5