9CY5

Dyrk1a bound to a competitive inhibitor

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	LIQUID ANODE
Source details	BRUKER METALJET
Temperature [K]	100
Detector technology	PIXEL
Collection date	2023-11-30
Detector	Bruker PHOTON III
Wavelength(s)	1.34
Spacegroup name	P 21 21 21
Unit cell lengths	64.886, 84.646, 148.799
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	24.810 - 2.490
R-factor	0.20254
Rwork	0.200
R-free	0.25894
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	1.782
Data reduction software	PROTEUM2
Data scaling software	Aimless
Phasing software	REFMAC
Refinement software	REFMAC (5.8.0425)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	24.810	2.590
High resolution limit [Å]	2.490	2.490
Rmerge	0.213	0.890
Number of reflections	29304	3066
<I/σ(I)>	10.6
Completeness [%]	99.1
Redundancy	10.2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		293	1.8 M SODIUM MALONATE, 1.3% PEG 400, PH 6.0