9YIC
Crystal structure of human IL-17A in complex with Compound 1
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 17-ID |
| Synchrotron site | APS |
| Beamline | 17-ID |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2016-03-21 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 1.0 |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 167.930, 122.690, 52.840 |
| Unit cell angles | 90.00, 93.82, 90.00 |
Refinement procedure
| Resolution | 35.533 - 3.150 |
| R-factor | 0.2163 |
| Rwork | 0.215 |
| R-free | 0.24210 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.002 |
| RMSD bond angle | 0.603 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | PHASER |
| Refinement software | PHENIX (dev_1428) |
Data quality characteristics
| Overall | Inner shell | Outer shell | |
| Low resolution limit [Å] | 49.500 | 49.500 | 3.230 |
| High resolution limit [Å] | 3.150 | 14.090 | 3.150 |
| Rmerge | 0.069 | 0.012 | 0.872 |
| Rmeas | 0.082 | 0.014 | 1.028 |
| Number of reflections | 18428 | 211 | 1339 |
| <I/σ(I)> | 15.88 | ||
| Completeness [%] | 99.3 | ||
| Redundancy | 3.4 | ||
| CC(1/2) | 0.998 | 1.000 | 0.688 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 295.15 | 13.7% PEG 6000, 0.1M sodium malonate pH 4.0, 1.3% methyl-2,4-pentanediol |
