9VM9

Crystal structure of FGFR3 in complex with 10s

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL10U2
Synchrotron site	SSRF
Beamline	BL10U2
Temperature [K]	80
Detector technology	CCD
Collection date	2025-05-12
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.97918
Spacegroup name	P 1 21 1
Unit cell lengths	58.700, 113.510, 87.900
Unit cell angles	90.00, 94.97, 90.00

Refinement procedure

Resolution	17.930 - 2.650
R-factor	0.2621
Rwork	0.259
R-free	0.31250
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.002
RMSD bond angle	0.585
Data reduction software	XDS
Data scaling software	XDS
Phasing software	PHENIX
Refinement software	PHENIX ((1.19.2_4158: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	69.330	2.744
High resolution limit [Å]	2.650	2.650
Number of reflections	33046	3312
<I/σ(I)>	5.67	2.22
Completeness [%]	98.8
Redundancy	5.7
CC(1/2)	0.910	0.443

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	7.5	293	25% (w/v) PEG 3350, 0.2 M MgCl2, and 0.1 M HEPES, pH 7.5