9GOH

Crystal structure of DPP4 in complex with sulphostin.

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2022-10-18
Detector	DECTRIS EIGER X 16M
Wavelength(s)	0.99998
Spacegroup name	P 21 21 21
Unit cell lengths	65.920, 68.208, 421.060
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	210.530 - 2.380
R-factor	0.23625
Rwork	0.236
R-free	0.28547
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.003
RMSD bond angle	1.344
Data reduction software	autoPROC
Data scaling software	autoPROC ((Version 1.1.7))
Phasing software	PHASER
Refinement software	REFMAC (5.8.0267)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	210.530	2.420
High resolution limit [Å]	2.380	2.380
Number of reflections	78066	3786
<I/σ(I)>	14.5
Completeness [%]	99.9
Redundancy	8.2
CC(1/2)	0.990	0.910

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		293	BICINE: 0.10 M pH:9.00 ; LiSO4: 0.16M ; PEG 2K MME: 24 %w/v