9GDI
HUMAN PI3KDELTA IN COMPLEX WITH ISOCUMARIN INHIBITOR 10
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2013-12-04 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 0.99998 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 90.474, 108.618, 142.402 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 86.360 - 2.810 |
| R-factor | 0.24695 |
| Rwork | 0.246 |
| R-free | 0.29897 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.007 |
| RMSD bond angle | 1.035 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | MOLREP |
| Refinement software | REFMAC (5.6.0117) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 86.360 | 3.060 |
| High resolution limit [Å] | 2.810 | 2.810 |
| Rmerge | 0.035 | 0.451 |
| Number of reflections | 34545 | 7702 |
| <I/σ(I)> | 25.25 | |
| Completeness [%] | 99.0 | |
| Redundancy | 5.2 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 293 | 16% PEG6000, 0.10 M KCL, 0.10 M MES |
