9FWX

Crystal structure of BRD4 BD1 with MEN1404BS.

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X06SA
Synchrotron site	SLS
Beamline	X06SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2011-11-10
Detector	DECTRIS PILATUS 2M
Wavelength(s)	1.00002
Spacegroup name	P 21 21 21
Unit cell lengths	37.060, 44.390, 78.600
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	38.650 - 1.250
R-factor	0.1805
Rwork	0.180
R-free	0.19010
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	0.910
Data reduction software	XDS
Data scaling software	XSCALE
Phasing software	BUSTER
Refinement software	BUSTER (2.11.2)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	38.650	1.300
High resolution limit [Å]	1.250	1.250
Rmeas	4.700	18.200
Number of reflections	36386	3809
<I/σ(I)>	23.73
Completeness [%]	99.3	95.2
Redundancy	6.07

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	7.5	293	16.5 % PEG 3350, 0.1 M sodium nitrate, 8 % ethylene glycol