9FKX
Crystal structure of IL-17A in complex with compound 18
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X10SA |
| Synchrotron site | SLS |
| Beamline | X10SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2022-10-17 |
| Detector | DECTRIS EIGER X 16M |
| Wavelength(s) | 1.00000 |
| Spacegroup name | C 2 2 21 |
| Unit cell lengths | 64.550, 85.049, 119.483 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 59.740 - 2.048 |
| R-factor | 0.2303 |
| Rwork | 0.229 |
| R-free | 0.25240 |
| Structure solution method | FOURIER SYNTHESIS |
| RMSD bond length | 0.009 |
| RMSD bond angle | 0.980 |
| Data reduction software | autoPROC |
| Data scaling software | Aimless |
| Phasing software | BUSTER |
| Refinement software | BUSTER (2.11.8) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 59.742 | 2.083 |
| High resolution limit [Å] | 2.048 | 2.048 |
| Rmerge | 0.056 | 3.359 |
| Rmeas | 0.059 | 3.534 |
| Rpim | 0.019 | 1.086 |
| Number of reflections | 21069 | 1016 |
| <I/σ(I)> | 16.9 | 0.7 |
| Completeness [%] | 100.0 | 99.9 |
| Redundancy | 10 | 10.4 |
| CC(1/2) | 0.999 | 0.497 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 293 | 0.1M citrate pH 5.5 10% PEG 10,000 12% isopropanol 10% ethylene glycol |
