9CUO

Crystal structure of CRBN with compound 3

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	CLSI BEAMLINE 08ID-1
Synchrotron site	CLSI
Beamline	08ID-1
Temperature [K]	100
Detector technology	PIXEL
Collection date	2017-09-27
Detector	DECTRIS PILATUS 6M
Wavelength(s)	1.0332
Spacegroup name	F 2 2 2
Unit cell lengths	141.470, 141.500, 141.590
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	42.720 - 1.600
R-factor	0.15764
Rwork	0.155
R-free	0.20491
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.010
RMSD bond angle	1.595
Data reduction software	XDS
Data scaling software	HKL-2000
Phasing software	REFMAC
Refinement software	REFMAC (5.8.0238)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	42.720	1.657
High resolution limit [Å]	1.600	1.600
Rmerge	0.038	0.290
Rmeas	0.054	0.410
Rpim	0.038	0.290
Number of reflections	92235	9291
<I/σ(I)>	12.25	2
Completeness [%]	99.9	99.92
Redundancy	1.9
CC(1/2)		0.668

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP	4.7	291	0.1M Acetate, pH4.7, 0.2M sodium chloride, 1.1M ammonium sulfate