8WE3

Crystal structure of human FABP4 complexed with C7

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL02U1
Synchrotron site	SSRF
Beamline	BL02U1
Temperature [K]	100
Detector technology	PIXEL
Collection date	2023-04-07
Detector	DECTRIS EIGER2 S 9M
Wavelength(s)	0.9792
Spacegroup name	P 21 21 21
Unit cell lengths	32.437, 54.171, 75.492
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	27.830 - 1.820
R-factor	0.1989
Rwork	0.198
R-free	0.22760
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.002
RMSD bond angle	0.495
Data reduction software	XDS
Data scaling software	XDS
Phasing software	PHASER
Refinement software	PHENIX ((1.17.1_3660: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	27.830	1.885
High resolution limit [Å]	1.820	1.820
Number of reflections	12426	1200
<I/σ(I)>	10.9
Completeness [%]	99.5
Redundancy	2
CC(1/2)	0.993	0.743

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		293	1.6M trisodium citrate, PH6.5