8V8Z
Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3473329
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 31-ID |
| Synchrotron site | APS |
| Beamline | 31-ID |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2017-03-30 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 0.97931 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 37.755, 75.179, 93.314 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 30.000 - 2.010 |
| R-factor | 0.21898 |
| Rwork | 0.217 |
| R-free | 0.25973 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.008 |
| RMSD bond angle | 1.199 |
| Data reduction software | MOSFLM |
| Data scaling software | SCALA |
| Phasing software | PHASER |
| Refinement software | REFMAC (5.8.0135) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 35.000 | 2.120 |
| High resolution limit [Å] | 2.010 | 2.010 |
| Number of reflections | 18167 | 2580 |
| <I/σ(I)> | 14.1 | |
| Completeness [%] | 99.3 | 98.7 |
| Redundancy | 7.3 | 7.5 |
| CC(1/2) | 0.997 | 0.929 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 4.5 | 294 | 30% PEG 300, 100mM Sodium Acetate pH 4.5 |
