8DYG

IL17A homodimer bound to Compound 7

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	CLSI BEAMLINE 08ID-1
Synchrotron site	CLSI
Beamline	08ID-1
Temperature [K]	100
Detector technology	CCD
Collection date	2016-05-11
Detector	RAYONIX MX-300
Wavelength(s)	1.00
Spacegroup name	C 1 2 1
Unit cell lengths	170.036, 35.819, 45.509
Unit cell angles	90.00, 98.23, 90.00

Refinement procedure

Resolution	28.760 - 1.490
R-factor	0.2118
Rwork	0.211
R-free	0.23280
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	4hr9
RMSD bond length	0.005
RMSD bond angle	1.010
Data reduction software	autoPROC
Data scaling software	Aimless
Phasing software	PHASER
Refinement software	PHENIX (1.19.2_4158)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	42.300	1.495
High resolution limit [Å]	1.490	1.490
Number of reflections	40316	1101
<I/σ(I)>	14.3	1.9
Completeness [%]	90.0
Redundancy	3.6
CC(1/2)	1.000	0.641

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION		290.15	1.6-2.0M Sodium Formate, 0.1M Tris, pH 7.8-8.8