8BWT

Structure of a symmetrical internal loop motif with three consecutive U:U mismatches from stem-loop 1 in the 3'-UTR of the SARS-CoV2 genomic RNA

Spectrometer

Experimental method: SOLUTION NMR

Spectrometer ID	Spectrometer maker	Spectrometer model	Spectrometer type	Spectrometer field strength
1	Bruker	AVANCE		600
2	Bruker	AVANCE		700
3	Bruker	AVANCE		800
4	Bruker	AVANCE		900

Experiment

experiment id	conditions id	solution id	Experiment type
1	1	2	2D 1H-15N HSQC
10	1	3	H(C)N aliphatic
11	2	3	H(C)P-CCH-TOCSY
12	1	2	H(N)CO
13	1	3	3D HCCH-COSY
14	1	3	3D HCCH-TOCSY
15	1	3	HCC-TOCSY-CCH-E.COSY
16	1	2	3D 1H-13C NOESY aromatic
17	1	2	3D 1H-13C NOESY aliphatic
18	1	3	3D 1H-13C NOESY aromatic
19	1	3	3D 1H-13C NOESY aliphatic
2	1	1	2D 1H-1H NOESY
3	1	2	2D 1H-13C HSQC aromatic
4	1	2	2D 1H-13C HSQC aliphatic
5	1	3	2D 1H-13C HSQC aliphatic
6	1	2	2D 1H-15N HSQC NH2 only
7	1	2	H56C56(C4N3)H optimized for H56
8	1	2	H56C56(C4N3)H optimized for C56
9	1	3	H(C)N aromatic

NMR Sample

conditions id	NMR sample pH	NMR sample pressure	NMR sample temperature
1	6.2	1	283
2	6.2	1	298

Conformers

Conformers Calculated Total Number	100
Conformers Submitted Total Number	10