8PUX
TEAD2 with a covalent inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ESRF BEAMLINE BM30A |
| Synchrotron site | ESRF |
| Beamline | BM30A |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2023-06-10 |
| Detector | DECTRIS PILATUS 6M-F |
| Wavelength(s) | 0.9697 |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 122.306, 61.613, 79.704 |
| Unit cell angles | 90.00, 117.55, 90.00 |
Refinement procedure
| Resolution | 54.280 - 2.050 |
| R-factor | 0.22152 |
| Rwork | 0.220 |
| R-free | 0.26051 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.008 |
| RMSD bond angle | 1.474 |
| Data reduction software | XDS |
| Data scaling software | XDS |
| Phasing software | PHASER |
| Refinement software | REFMAC (5.8.0267) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 54.280 | 2.120 |
| High resolution limit [Å] | 2.050 | 2.050 |
| Number of reflections | 33152 | 3290 |
| <I/σ(I)> | 11.63 | |
| Completeness [%] | 99.7 | |
| Redundancy | 1.9 | |
| CC(1/2) | 0.999 | 0.907 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 298 | 2.8M sodium formate |
