8PON

TEAD2 in complex with an inhibitor

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE
Temperature [K]	100
Detector technology	PIXEL
Collection date	2023-06-10
Detector	DECTRIS PILATUS3 6M
Wavelength(s)	0.9697
Spacegroup name	I 1 2 1
Unit cell lengths	80.117, 61.591, 111.292
Unit cell angles	90.00, 102.57, 90.00

Refinement procedure

Resolution	53.580 - 2.200
R-factor	0.212
Rwork	0.210
R-free	0.25440
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	0.978
Data reduction software	XDS
Data scaling software	XDS
Phasing software	PHASER
Refinement software	PHENIX ((1.20.1_4487: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	53.580	2.280
High resolution limit [Å]	2.200	2.200
Number of reflections	26936	2647
<I/σ(I)>	7.22
Completeness [%]	99.5
Redundancy	2
CC(1/2)	0.996	0.598

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		298	2.8M sodium formate