8PAS
Crystal structure of MAP4K1 with a SMOL inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X10SA |
| Synchrotron site | SLS |
| Beamline | X10SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2017-06-01 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 0.99998 |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 61.040, 100.056, 61.055 |
| Unit cell angles | 90.00, 102.03, 90.00 |
Refinement procedure
| Resolution | 42.910 - 2.700 |
| R-factor | 0.23093 |
| Rwork | 0.228 |
| R-free | 0.29970 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.011 |
| RMSD bond angle | 1.887 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | PHASER |
| Refinement software | REFMAC (5.8.0267) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 42.910 | 2.950 |
| High resolution limit [Å] | 2.700 | 2.700 |
| Rmeas | 0.049 | 0.529 |
| Number of reflections | 19051 | 4477 |
| <I/σ(I)> | 21.55 | 3.5 |
| Completeness [%] | 96.1 | 97 |
| Redundancy | 3 | 3.1 |
| CC(1/2) | 0.999 | 0.936 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 293 | NOT DISCLOSED |
