8OVZ

Crystal structure of D1228V c-MET bound by compound 16

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SOLEIL BEAMLINE PROXIMA 1
Synchrotron site	SOLEIL
Beamline	PROXIMA 1
Temperature [K]	100
Detector technology	PIXEL
Collection date	2017-08-31
Detector	DECTRIS PILATUS 6M
Wavelength(s)	0.97857
Spacegroup name	P 21 21 21
Unit cell lengths	53.900, 56.670, 215.810
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	39.080 - 2.206
R-factor	0.227
Rwork	0.225
R-free	0.27490
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.007
RMSD bond angle	0.870
Data reduction software	XDS
Data scaling software	XDS
Phasing software	PHASER
Refinement software	BUSTER (2.11.8 (8-JUN-2022))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	44.520	2.260
High resolution limit [Å]	2.210	2.210
Number of reflections	33771	2380
<I/σ(I)>	7.4
Completeness [%]	98.8
Redundancy	4.8
CC(1/2)	0.992	0.653

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		293	12 % PEG 8000, 200 mM NH4I, 0.1 M PCPT pH 7