8RQU

Structure of TEM1 beta-lactamase variant 70.a

Replaces:  8OF9

Summary for 8RQU

• Entry DOI: 10.2210/pdb8rqu/pdb
• Descriptor: Beta-lactamase TEM-1, MAGNESIUM ION (3 entities in total)
• Functional Keywords: class a tem-1 beta-lactamase, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 57133.23

Authors

Napie, E.,Fram, B.F.,Gauthier, N.P.,Sander, C.,Khan, A.R. (deposition date: 2024-01-19, release date: 2024-02-14)

• Primary citation: Fram, B.,Truebridge, I.,Su, Y.,Riesselman, A.J.,Ingraham, J.B.,Passera, A.,Napier, E.,Thadani, N.N.,Lim, S.,Roberts, K.,Kaur, G.,Stiffler, M.,Marks, D.S.,Bahl, C.D.,Khan, A.R.,Sander, C.,Gauthier, N.P.; Simultaneous enhancement of multiple functional properties using evolution-informed protein design.; Biorxiv, 2023; PubMed: 37214973; DOI: 10.1101/2023.05.09.539914

Experimental method

X-RAY DIFFRACTION (2.9 Å)