8C17

Crystal structure of TEAD4 in complex with peptide 1

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2022-09-05
Detector	DECTRIS EIGER2 X 16M
Wavelength(s)	1.000
Spacegroup name	P 31 2 1
Unit cell lengths	54.468, 54.468, 166.429
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	18.490 - 2.250
R-factor	0.2106
Rwork	0.209
R-free	0.23840
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	0.990
Data reduction software	autoPROC
Data scaling software	STARANISO
Phasing software	PHASER
Refinement software	BUSTER (2.11.8 (8-JUN-2022))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	24.450	2.340
High resolution limit [Å]	2.250	2.250
Rmerge	0.112	1.332
Number of reflections	12749	639
<I/σ(I)>	12	2.2
Completeness [%]	89.4
Redundancy	15
CC(1/2)	0.998	0.819

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		293	2.4 M sodium malonate