8A0U

Crystal structure of TEAD3 in complex with CPD4

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2015-12-12
Detector	DECTRIS PILATUS 6M
Wavelength(s)	1.0000
Spacegroup name	P 21 21 21
Unit cell lengths	65.265, 128.607, 156.107
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	24.640 - 2.895
R-factor	0.2144
Rwork	0.212
R-free	0.26800
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	Previous in-house structure
RMSD bond length	0.008
RMSD bond angle	1.000
Data reduction software	autoPROC
Data scaling software	STARANISO
Phasing software	PHASER
Refinement software	BUSTER (2.11.8 (3-FEB-2022))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	24.638	2.980
High resolution limit [Å]	2.895	2.895
Rmerge	0.158	0.741
Number of reflections	27738	1388
<I/σ(I)>	10.5	2.4
Completeness [%]	92.2
Redundancy	6.5
CC(1/2)	0.997	0.823

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		293	1.1 - 1.4 M sodium/potassium phosphate pH 5.6