7RXL

Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 23-ID-B
Synchrotron site	APS
Beamline	23-ID-B
Temperature [K]	100
Detector technology	PIXEL
Collection date	2017-10-28
Detector	DECTRIS EIGER X 16M
Wavelength(s)	1.03320
Spacegroup name	P 1
Unit cell lengths	40.685, 69.337, 93.214
Unit cell angles	85.06, 78.14, 79.18

Refinement procedure

Resolution	39.207 - 1.823
R-factor	0.2087
Rwork	0.206
R-free	0.25530
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	Homology model
RMSD bond length	0.009
RMSD bond angle	0.782
Data reduction software	HKL-2000
Data scaling software	SCALEPACK
Phasing software	PHASER
Refinement software	PHENIX ((1.14_3260: ???))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	50.000	1.850
High resolution limit [Å]	1.820	1.820
Rpim	0.065	0.612
Number of reflections	82577	3628
<I/σ(I)>	10.6	1
Completeness [%]	95.3	84
Redundancy	2.6
CC(1/2)	0.891	0.630

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP	6.9	293.15	20% PEG3350, 0.2 M potassium chloride, pH 6.9