7B3V
Crystal structure of c-MET bound by compound 3
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | DIAMOND BEAMLINE I03 |
| Synchrotron site | Diamond |
| Beamline | I03 |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2017-06-01 |
| Detector | DECTRIS PILATUS 2M |
| Wavelength(s) | 0.97625 |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 111.646, 42.792, 86.137 |
| Unit cell angles | 90.00, 121.29, 90.00 |
Refinement procedure
| Resolution | 22.610 - 1.930 |
| R-factor | 0.226 |
| Rwork | 0.225 |
| R-free | 0.24800 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | internal |
| RMSD bond length | 0.010 |
| RMSD bond angle | 1.010 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.6) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 28.710 | 1.960 |
| High resolution limit [Å] | 1.930 | 1.930 |
| Number of reflections | 26013 | 1206 |
| <I/σ(I)> | 18.8 | |
| Completeness [%] | 98.0 | |
| Redundancy | 3.2 | |
| CC(1/2) | 0.993 | 0.936 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 273 | 25 % PEG3350, 0.2 M (NH4)2SO4, PCPT pH 5.5 |
