7L26

HPK1 IN COMPLEX WITH COMPOUND 38

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2019-05-03
Detector	DECTRIS PILATUS 6M
Wavelength(s)	1.00002
Spacegroup name	P 1
Unit cell lengths	58.138, 58.168, 98.955
Unit cell angles	89.84, 90.13, 97.60

Refinement procedure

Resolution	98.950 - 2.300
R-factor	0.2627
Rwork	0.262
R-free	0.29830
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	PREVIOUSLY SOLVED STUCTURE
RMSD bond length	0.013
RMSD bond angle	1.666
Data reduction software	XDS
Data scaling software	XSCALE
Refinement software	REFMAC (5.8.0155)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	98.950	2.550
High resolution limit [Å]	2.300	2.300
Rmeas	0.092	0.568
Number of reflections	54548	14634
<I/σ(I)>	8.65	2.56
Completeness [%]	95.0	95.4
Redundancy	2.2	2.2
CC(1/2)	0.997	0.998

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION		293	UNDISCLOSED