7UUT

Ternary complex crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus mutants C295A and I86A provides better understanding of catalytic mechanism

Replaces:  7JNU

Summary for 7UUT

• Entry DOI: 10.2210/pdb7uut/pdb
• Descriptor: Secondary-alcohol dehydrogenase, ZINC ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total)
• Functional Keywords: secondary alcohol dehydrogenases, nadp, 2-pentanol, oxidoreductase
• Biological source: Thermoanaerobacter pseudethanolicus; More
• Total number of polymer chains: 4
• Total formula weight: 154439.44

Authors

Dinh, T.,Phillips, R.,Rahn, K. (deposition date: 2022-04-28, release date: 2022-05-11, Last modification date: 2023-10-18)

• Primary citation: Dinh, T.,Rahn, K.T.,Phillips, R.S.; Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.; Proteins, 90:1570-1583, 2022; PubMed: 35357038; DOI: 10.1002/prot.26339

Experimental method

X-RAY DIFFRACTION (1.89 Å)